Re: I believe....
"Given how big Apple is in certain industries, the software for those industries *will* follow. Besides, Apple has a track record of ensuring transitions such as these go smoothly. I wouldn't be surprised if in many cases all you needed to do was to change the compilation target"
That will almost certainly not be the case and Apple will take a software hit at the professional end of things not least because a lot of scientific software relies on cross platform open source standards that Apple is now completely abandoning. In addition, Autodesk will no longer be producing their Alias and VRED software for Macs and that is just the start of what is to come as a direct result of Apple's voluntary move to Arm architecture.
I've seen this happen numerous times on Apple forums where professionals have been displeased by the performance of the Mac butterfly keyboards and gimmicks like the touch bar so much so that they've left the entire Apple ecosystem, iPhones included and they've taken their families with them. More of that type of desertion is almost certainly on its way.