I use ad blocker at home but....
I feel guilty using an ad blocker for The Reg, and a few other sites but it make the articles easier to read.
I don't have an ad blocker at work as the machines are managed elsewhere and installing plugins are frowned on. That means I see the ads on el Reg, and elsewhere. And most are so tuned to grab your attention that they are an obnoxious interference to point of making me cry. Between autoplay, colour saturation, and other techniques it makes me want to raze the ad mediation services.
And even with ad blockers we still have data exfiltration. Even with my custom rules in my firewall I still know, from what I'm presented with, that blocking is not perfect.
Alas, I do not see an end to this issue.