Debian
I am running Debian testing MATE since 2011, on 2 pc's and 2 laptops, the only issue I had was when they suddenly removed the fglrx drivers (I had 2x HD7870 running in CrossFire) for the Radeon drivers.
For me Debian testing is the somewhat rolling Debian distro. Reliable and stable as a desktop for server use I would just stick with Debian stable and maybe with some backports if needed.
My NAS a QNAP TS-459Pro is running Debian bullseye (stable), QNAP's support ended years ago, in the OpenMediaVault flavour and will upgrade to bookworm when OMV is ready.
It serves my purpose.