HelpMaster works great for us.
Give HelpMaster a try. http://www.helpmasterpro.com a try.
It has one of the best email automation platforms available, with full text parsing, attachment scanning and multi-profile scanning.
Windows + Web. Knowledge base that can be published to the web, then rated, ranked and filtered.
Comprehensive workflow, Active Directory synchronization (including photos), asset management.
...and easy to install, configure and use.
Highly recommended.