Re: Epi feat
There are more practical reasons. This is a bit like saying "get 12% extra RAM by using those ECC bits".
Biology doesn't put methyl groups on DNA for prettyfication, it is a marker for a purpose (e.g. defence against pathogens, turning some genes on or off in response to environment... there is a whole field called epigenetics dealing with this). So if you use a biological system to process or reproduce this DNA, you'll have to be sure the data isn't erased or corrupted. At that point you might be better just redesigning the system from the ground up with non-natural bases etc.
Incidentally if you want to compare I'd say DNA is more like tape backup, as it not infrequently needs to be unwound from histones to be read. It's also more stable then you would think, because of the deoxy function which slows down non-biological degradation hugely. RNA, especially mRNA is more like RAM, it is used for working copies and has a much shorter biological lifetime.
Of course it is the sort of work that raises institutional profiles and gets good publicity, so can't blame the boffins for milking it a bit.