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However - didnt Nostromo looked something like this: http://time.absoluteavp.com/pics/nostromo.jpg?
BTW - how to generate (or handle) gravity will be a deciding factor for ship designs, and if the technology comes around to artificially generate gravity, all bets are off. Sometimes current boffins seems to have too narrow scope...
On the other hand - if your spaceship needs to have atmospheric capabilities, a round shape (or disc shape) is not totally off - why waste more fuel/energy?