DEP Breaks Most Remaining Reasons to Use IE
The only reason to use IE in a corporate environment are legacy ActiveX controls. Unfortunately, DEP "breaks" many of those and a bunch of add-in's as well. Unfortunately, DEP is an "all or nothing" setting, you cannot selectively disable it for "trusted" or internal sites.
I've been trying to push for Firefox at our company, and implement IE Tabs when we have no choice but to use IE. Since Firefox configuration can't be managed through GPO's, it has been a difficult sell to the guys that manage the workstations and AD.
The quality and security of the computing experience seems to be nosediving as we plummet headlong into the "browser is the OS" mentality.
Mine's the one with the application installation CD, that I can install and not worry about whatever goddam browser or plug-in revision I have. Bring back statically linked executables. You can keep all of your frameworks, dynamic libraries, shared objects, JVM's, Silverlight/Flash and 50 other ways to waste my time guessing whether my app will work or not. Get off my lawn.