I was spraffing away about nothing on a forum decades ago and I got a short reply from a woman in Switzerland who said she had LIS. I asked what that meant, and fours hours later, with intensive effort and the help of her nurse she explained.
It seemed hellish to me, worse than death. She could only move her eyes, only communicate with her eye movements. She said the internet was her lifeline to sanity. Idiotic me said I'm an electronics engineer with time and money, I'll be able to develop something to help her get back some control. Took me 20 seconds to make that worthless promise, took her hours to thank me.
She disappeared days later. That's the thing with LIS, maintaining contact is like clinging to jetsam in the atlantic, eventually you lose hope and let go. I don't think she ghosted me, she just sank.
I don't have a design for a chip to help LIS patients. Maybe eye monitoring is a better way to go over brain monitoring. I just know it is worth pursuing.
I do know there are many far smarter engineers than me at El Reg. I'd suggest this as a worthy project for 40 free open source chips.
There is a book/movie that came out since, "The Diving bell and the Butterfly". You might not find it sympathetic because the author was a fashionista, but it can happen to anyone. One minute you are you, then you are a sack of potatoes.