Comparing oranges and elephants again!
If you are SME and all you need is a simple mail/calendaring application, stick to Exchange/Outlook.
Notes/Domino is so much more than just mail and the real value is not realised until the collaborative, workflow and data storage functions are properly developed. Unlike MS, this all comes in one box from Lotus.
I have worked in both Domino and Exchange environments and will opt for Domino anytime. It astounds me that users in an Exchange environment actually tolerate the quality and level of service I have witnessed. Indeed, those users who have moved to our organisation from Exchange environments invariably comment on the improvement to their working lives.
Note/Domino does NOT need the client to operate - it is easily switched to web access.
Domino will support Outlook for those who need this comfort blanket.
The Notes Client is endlessly adaptable - to the extent that it can even be made to look and operate like Outlook. How customisable is Outlook? Outlook is a triumph of form over function.
Domino Admin is hardly rocket science - this means that personnel who understand business priorities can be quickly trained to take control away from the techie taliban.
Domino Designer allows simple applications to be designed quickly, easily and without a PHD in advanced computer science. Adaptation of the many supplied database templates is simplicity itself.
The licensing model: simplicity, clarity and future-proofed. Just what the doctor ordered.
Our Domino Environment has multiple servers and availability (over 10 years) is 99.99% with any outages being caused by server platform (MS), network switching or power supply problems.