iTunes - *FEH*!
One of the reasons I don't use an iPod is because iTunes is such a vile piece of crap.
The others are that iPlods don't support Vorbis and FLAC, and don't have proper replaceable batteries. Only designs that are cheap and disposable can be excused for having a non-replaceable battery (the iPod Shuffle, for instance). In any other case, it's planned obsolescence to "encourage" people to buy another unit instead of simply replacing a worn-out battery.