We had a lady that looked after conference rooms etc. After a year or so she became very protective of them, they were "her turf".
It got to the stage where if she wasn't there you couldn't use any of the rooms, including if she was away for 2 weeks holiday she'd take the keys with her, or would hide them somewhere in the office without telling anyone.
The manager ended up telling us to drill the locks out to gain access. She wasn't pleased when she got back from her holiday.