Gutenberg's printing press did immense harm - short term
The most spectacular example of the harm done by printing was Malleus Maleficarum. It was an early best seller (the first bar the Bible, I think) which played a major role in reiving beleife in witchcraft. It would be a bit much to just blame that one book, but it was very influential and changed a lot of people's views.
The contemporary parellels would be things like people thinking covid vaccines are a plot by Bill Gates to control them because they "read it on the internet".
Not that books and newspapers cannot be used to circulate tosh too!