In the early years of my career I suffered a major stress-related collapse which took me almost three years to fully recover from. One of the first things I remember thinking when I woke up was 'nobody is doing that to me again'. Since then, work has simply been a means to provide money to do what I want. I walk out the office (or as it is now, close the laptop) and that's me gone until start-time tomorrow. Career? I decided I didn't want one after that. In the fifteen years I've had my current job my manager has called once out-of-hours and apologised profusely before asking the question. It took longer to listen to his apology than it did to answer the question.
As so many above have said: it ain't worth it.