What could possibly go wrong? A. Just look around you.
Bacteria quite literally chop and [ex]change chunks of DNA all the time [1]. It's only because most mutations are deleterious that E. coli isn't like one of those super-evolving life forms from the HHGTTG. So I see two problems - (a) each instantiation of a datastore (as opposed to a functional gene) in a cell will be subject to random changes considerably more frequent than e.g. radiation-induced mutation, and (b) a segment of a cute cat video gets spliced into an actual gene, and turns out to encode for the Ravenous Bug-blatter Beast of Traal.