I block adverts with Steven Black's Hosts file; minus the censorship options, fakenews & social, and I use Twitter frequently * --- never had a any adverse consequence from the firm.
With the social option, many Twitter functions were affected until I obviated that option, but I'm sure Twitter never noticed. I really didn't know Twitter has advertisements. Just like a number of social sites. I'm not living in 1998.
* I only use it to 'follow' various manga artists, etc., as a way of thanking them; not for any serious reading, such as reading recent American presidents' dumb thoughts. Or those of our appalling own MPs.