Echo chamber aside
You know, you can simply google stuff! You don't need to echo The Registers endless sarcasm, or Fox News' "Trump is the real victim of Covid19" drivel.
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The studies relating to Covid 19:
https://en.wikipedia.org/wiki/Hydroxychloroquine
"Hydroxychloroquine is also studied as an experimental treatment for coronavirus disease 2019 (COVID-19).[3] Some are also using it off label for the disease.[32]"
"A randomized controlled trial on 30 patients by Chinese researchers showed that hydroxychloroquine "didn’t shorten the time to SARS-CoV-2 clearance".[33][34] Also, in the study patients were being treated with several other treatments (such as lopinavir/ritonavir or umifenovir) at the same time as the hydroxychloroquine treatment, making it difficult interpret the results.[33]"
"A study of 36 patients in Marseille, France, showed a reduction in viral load, but its methodology was criticized.[35] The patients were not randomized, the analysis excluded three patients in the treatment group who were transferred to an intensive care unit and one who died,[36] and the study was published in a journal whose editor-in-chief is one of the article's authors.[37]"
"In vitro studies in cell cultures demonstrated that hydroxychloroquine was more potent than chloroquine against SARS-CoV-2.[38][39] On 17 March 2020, the AIFA Scientific Technical Commission of the Italian Medicines Agency expressed a favorable opinion on including the off-label use of chloroquine and hydroxychloroquine for the treatment of COVID-19.[40] "
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My Takeaway on the mechanism of action:
Looking at the mechanism of action, it seems to dampen the immune system. I read Covid 19 in the lower lung is so aggressive that the immune system cannot distinguish infected cells from nearby cells and kills everything. I assume, from this mechanism, that its use is to lessen the immune response in that case? Which would be hit or miss, you'd presumably only administer it when the immune response is killing the patient? Otherwise it would make things worse!?
Is there a clinician here who can spell the assume mechanism?
Biting the hand that feeds IT
