Re: Use
Yes.
BOINC and GIMPS.
BOINC, https://boinc.berkeley.edu/ , for bragging rights and to "help Humanity" and GIMPS https://www.mersenne.org/ to "help Humanity" and possibly Win Big Prizes.
The more RAM, CPU and GPU you can chuck at those two the better your odds of curing cancers, unwrapping proteins, finding neutron starts, decoding Alien Spam, mapping the Galaxy, finding Mersenne Primes or just heating your house.