You can run DoH over a VPN... or just plain old DNS over a VPN for a similar effect.
In any case you need to trust someone, be it your ISP (*cough* don't *cough*), your VPN provider (hm, maybe), your DoH endpoint provider (hm), the website, and so on. If you want real privacy though, at some point you'll be better just using Tor, I2P or similar.