14 PCs in this office - over 50 in the building - over 60 if you include virtuals. Various specs from elderly compact dell desktops to high end ultra-books and everything has updated fine. All running Sophos. Some took a while (longest was just under an hour and a half) but mostly fine.
I also have 8 Pcs in the house and only one caused any kind of issues. This was a laptop that had some major issues and the motherboard was replaced under warranty and the hard drive was imaged swapped over with an SSD recently so there could have been some kind of serial number check that went wrong.