Re: 45 days vs 365
"routine service to check for airframe fatiuge/damage."
ISTR that the biggest concern for airframes is pressure cycles. On a long flight duration drone A) there's no pressure cycling to speak of. B) there's probably no pressure vessel C) there's no self-loading cargo to complain if the pressure vessel fails.
Running an engine for a year straight might raise some concerns, but continuous-duty electrical motors are a thing that exists.