Go all the way I say
Maybe we can see the return of those ultimate makeover party people from customize.org, windowblinds, bb4win, litestep and friends; these helpful people would give you enough tools to replace winfile.exe and give your desktop the look of a totally different computer that looked like it was made by UX/UI designers that had gone to interface heaven.
If you were a winamp fan or an early linux adopter, you could find ways to make your workplace computer behave like your *nix box.
But that was then