" [...] why does Deckard need the slow and unwieldy Voight-Kampff machine to spot a skin-job when replicants can pluck eggs from boiling water and have trademarks built into their skin cells?"
False positives? Because the tests you suggest would amount to torture when performed on an actual human. And hopefully, in the future we won't do that anymore.
"Skin jobs". That's what Bryant called Replicants. In history books he's the kind of cop who used to call black men "niggers".