Ditch it already
Skip this generation and go to gen 6 jets. Selective acquisition of proven gen 4 airframes + better avionics and weapons should be able to hold the fort against China or Russia until 2025-2030, which is getting awfully close to F35 release. And remain amply sufficient against low tech opponents.
Cut the Marines and their VTOL out.
And whatever you do, write affordability into the reqs. While keeping a lookout for the possible rise of disruptive autonomous air combat drone capability.
Won't happen. The US is committed to this massive $$$ black hole that sucks up funding of any alternatives and too many careers would be ruined by ditching it.