I have to say, Veeam Backup and Replication V7 (and now v8) is some awesome software for virtual machines. Used Vertitas/Symantec Backup Exec in the past and finding Veeam a lot better.
They also have a free Beta Endpoint backup out at the moment that's worth checking out if you need to backup individual machines, sadly not centrally managed, but still worthwhile:-
http://go.veeam.com/endpoint