back to article Man with artificial heart survives over 100 days outside hospital

Australian company BiVACOR has revealed a patient implanted with its artificial heart survived for 100 days – and is still with us after receiving a donated organ. The un-named man had heart disease that meant he needed a replacement ticker. BiVACOR makes just such a replacement that it calls the “Total Artificial Heart” (TAH …

  1. Anonymous Coward
    Anonymous Coward

    Still..

    .. these people would be dead without. I call that a serious win, respect for this development and the people that are working on it.

    1. John Robson Silver badge
      Boffin

      Re: Still..

      Pumping blood isn't easy - too many cells to get damaged if you aren't careful enough, so serious respect for making a device that small!

  2. seven of five Silver badge
    Joke

    Big deal...

    Pfff, big deal. Monster-in-law has been around for more than 60 years without any heart (or brain) at all. Don't get what all the fuss is about..

    1. Ken Shabby Bronze badge
      Terminator

      Re: Big deal...

      Gives the Tin Man a hope

  3. Jason Hindle Silver badge

    From 100 days to a lifetime?

    This is impressive. What a heart does is pretty straightforward in engineering terms, so any breakthrough in materials science/tribology could lead to something more practical and longer-lasting than a human heart transplant, which comes with all manner of risks and complications.

    1. A Non e-mouse Silver badge

      Re: From 100 days to a lifetime?

      Even in the 24th century artificial hearts have to be replaced occasionally.

    2. Snowy Silver badge
      Coat

      Re: From 100 days to a lifetime?

      The issues with making it last a lifetime could be down to how it is powered?

    3. SnailFerrous

      Re: From 100 days to a lifetime?

      All artificial hearts last a lifetime. It's in the guarantee! The clever bit is making that lifetime a long one.

      1. Dave559

        Re: From 100 days to a lifetime?

        "All artificial hearts last a lifetime. It's in the guarantee! The clever bit is making that lifetime a long one."

        All biological hearts last a lifetime. It's in the guarantee! The difficult bit is that the duration of the guarantee period is not known in advance… ;-)

    4. DS999 Silver badge

      Re: From 100 days to a lifetime?

      What a heart does is pretty straightforward in engineering terms

      True, but we still struggle to build any sort of pump for any purpose that can continue to operate for a decade without interruption, let alone without regular maintenance (which would be undesirable, if it meant having to get your chest cut open every year)

      1. David 132 Silver badge
        Happy

        Re: From 100 days to a lifetime?

        This is one tech area where CI/CD or "move fast and break things" probably aren't the appropriate approach.

  4. Mentat74
    Coat

    TAH...

    Very much !

  5. Kerfufflinator
    Terminator

    Surely the “percutaneous driveline” could be replaced with a USB-C connector and the batteries held in the heart itself. Who wouldn't want to plug in before sleep as if they were a phone??

    All jokes aside, this is seriously amazing.

    1. Anonymous Coward Silver badge
      Flame

      Brings a whole new meaning to heartburn

    2. An_Old_Dog Silver badge

      USB-C Connector

      Great. Roll over in your sleep, bend or break the connector, and Bad Things™ happen.

    3. Dagg Silver badge

      They are actually looking at using induction through the skin to charge/power it. Similar to a mobile phone charger.

  6. Bebu sa Ware
    Windows

    100 days without a pulse.

    Absolutely brilliant biomedical engineering. From the model the two sides of the heart have separate rotary pumps for the different pressures required for the lung (low impedance) cf the body (high impedance) - clearly the flows are identical.

    I would be curious whether after things have settled down you would notice not having a pulse. Or indeed there are any pathologies associated with the absence of a pulse.

    I suspect we will be able to culture replacement hearts long before we will be able to construct mechanical hearts which have MTBF of the biblical three score and ten.

    1. HuBo Silver badge
      Alien

      Re: 100 days without a pulse.

      Yeah, Dick Cheney famously had a centrifugal left-ventricular assist device (LVAD) implanted that left him pulseless for almost 2 years until a transplant was available. Back then, the NYT wrote: "patients feel nothing unusual. But they are urged to [...] alert emergency room doctors as to why they have no pulse".

    2. DS999 Silver badge

      Re: 100 days without a pulse.

      there are any pathologies associated with the absence of a pulse

      Being declared dead if you were unconscious would be a big one. You'd definitely want to wear a medical alert bracelet!

      1. Richard 12 Silver badge

        Re: 100 days without a pulse.

        It's suspected that the stretch-release cycle helps ensure the arteries stay healthy, but nobody has gone without a pulse for long enough to really know whether this actually matters.

        1. DS999 Silver badge

          Re: 100 days without a pulse.

          That's a definite possibility, but it is also possible that a constant flow rather than a on/off would reduce issues from stuff like cholesterol deposits. So you never know.

  7. Missing Semicolon Silver badge

    turbulence

    I wonder if having a free-floating impeller means that the blades are constantly stirring the blood, and thus may cause coagulation in zones of high shear around the blade tips?

    1. HuBo Silver badge
      Alien

      Re: turbulence

      Indeed, the shear of red blood cells (that reduces their O₂-carrying capacity) is the challenge for centrifugal blood pumps iirc, while "volume displacement pumps" have challenges with valves (where clotting may occur). I have to guess that this here design is made to prevent excess shear while providing those 12 L/min (so that it works right).

      The use of MAGLEV tech in this BiVACOR TAH is also quite neat imho (as long as you don't carry your credit cards in a left-chest pocket ...)!

      1. An_Old_Dog Silver badge

        Magnetic Bearings

        My college roomie had a record turntable (Phillips?) which had magnetic bearings. It was neat to watch the turntable platter rise up an inch or so when you switched on the power.

  8. IGotOut Silver badge

    This is brilliant....

    ....but I just can't get the bat shit crazy film Crank 2 out of my head now.

    1. Dave559

      Re: This is brilliant....

      Harkonnen Industries are undoubtedly working on a 'plug-and-play' version as we speak: the perfect product to be sold to American (or Imperium) citizens who potentially might not pay their private medical bills [1] (oh, did we mention that plug-and-play means it is unplug-and-unplay as well?)…

      [1] «rolls eyes (albeit with some sympathy) in most-of-the-rest-of-the-developed-world-speak»

  9. Anonymous Coward
    Anonymous Coward

    Be interesting to know if a forever artificial heart is possible. I suspect it would need to rythmically pump as the body expects that and has evolved around pulsing.

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