By design?
Looking at the CISA list it looks more like by process to me. More of an agenda than a specification.
Secure is just correctness with a restricted set of concerns namely the specification's security properties.
It's the same old hard problem of verifiably correct software composing verifiably correct systems.
Secure by design should mean the construction of the system or software uses the specification of security properties as its primary design document which should also guide the construction processes with an eye to continuously verifying the product against the specification. Something like this, many years ago [1990], was called software or program derivation by analogy with the proof process in mathematics.
Considering the development processes and culture, quality control and sheer size of these players' code bases the CISA program is less a case of pissing into the wind than shitting in the face of a hurricane.
We will have fusion powered flying cars before we have secure correct software.