back to article Scientists suggest possible solution to space-induced bone loss

One of the foremost health risks for astronauts may have a cure en route. A specially-formulated medication has been shown to prevent bone loss in mice, and perhaps humans, aboard the International Space Station. According to the team from the University of California Los Angeles (UCLA) and the Forsyth Institute in Cambridge, …

  1. Munehaus

    Mice?

    These creatures you call mice, you see, they are not quite as they appear. They are merely the protrusion into our dimension of vast hyperintelligent pandimensional beings. The whole business with the cheese and the squeaking is just a front.

    1. Fr. Ted Crilly Silver badge

      Re: Mice?

      Munehaus the planet you lived on was commissioned, paid for, and run by mice. It was destroyed five minutes before the completion of the purpose for which it was built, and we've got to build another one."

      Only one word registered with Arthur.

    2. alisonken1
      Joke

      Re: Mice?

      Don't forget the documentary series Pinky and the Brain!

      (y/t link to intro)

  2. Filippo Silver badge

    Okay, space is cool, but surely the first target for this research would be osteoporosis sufferers on Earth? There are a lot of them.

    1. Roj Blake Silver badge

      From the article:

      "Burlington, Massachusetts-based Bone Biologics - appears to have reached the point of doing human clinical trials using NELL-1 to treat degenerative disk disease in a pilot program in Australia"

      1. Ken Shabby
        Facepalm

        I misread that as “Degenerative Dick Disease”, good to hear they have a potential cure

    2. Ordinary Donkey

      Now they've managed to make it 'cool' by giving it a space flight angle, maybe someone will get around to it at last.

    3. AVR

      And multiple myeloma sufferers. Biphosphonate does indeed have a bunch of side effects, notably odd pains, and normal dentists won't take you any more. I wonder how they solved that?

      1. lglethal Silver badge
        Joke

        and normal dentists won't take you any more. I wonder how they solved that?

        Mice dentists aren't so picky as human dentists...

  3. Jimmy2Cows Silver badge

    ...treatment for brain changes and other detrimental health effects of space exposure...

    It's long past time we spun something up in orbit to test whether centrifugal artificial gravity can actually counteract these (and other) microgravity effects. The whole "humans to Mars and beyond" concept is a lot more viable if it works.

    1. Greybearded old scrote

      Re: ...treatment for brain changes and other detrimental health effects of space exposure...

      Coriolis effects and other weirdness from rotation mean that you'd have to build big and rotate slowly. Don't think we can fund Babylon 5 (1km diameter rotating once per minute (yes, I'm geek enough to have measured that from the videos (and calculated that it gives a close enough result across 30 levels))) just yet.

      1. Jimmy2Cows Silver badge

        Re: ...treatment for brain changes and other detrimental health effects of space exposure...

        Yeah rotation radius is important to get the spin speed at or below 1RPM, which is generally accepted as the perceptible motion limit for most people. Depending on where you look on the web, calculations vary from around 200m to over 900m.

        But you don't have to build a Bab5 sized station to get that effect. A pair of small habitats separated by a long tether is enough. Spin up the pair around the centre of the tether. Same effect for minimal build mass (and associated fab/launch/deploy/maintain costs and complexities).

        That's enough to prove/disprove validity. If it pans out, scale up to larger, connected habs, and eventually fully cylindrical stations (O'Neill cyclinders etc.) from there. Attach big rocket motors and you have ships with artificial gravity. In theory, at least.

        1. Greybearded old scrote

          Re: ...treatment for brain changes and other detrimental health effects of space exposure...

          Yeah. Buzz Aldrin proposed a bolas design long ago. I just wanted to keep it short and sweet.

          1. Jimmy2Cows Silver badge

            Re: ...treatment for brain changes and other detrimental health effects of space exposure...

            Many, many such proposals over the last several decades. NASA doesn't seem interested, which is a bit surprising but I guess their budget is too small so they have to prioritise. At this rate the Chinese or Musk will do it first (actually there are proposals to thether a pair of Starships in bolas formation and spin 'em. Once Starship can launch without annihilating its launch pad and RUDing itself mid-flight, that is - rocket engineering is hard and it's early days for Starship).

        2. SonofRojBlake

          Re: ...treatment for brain changes and other detrimental health effects of space exposure...

          Or ONE habitat and a longer tether, with the much-lower-mass counterweight further out. The counterweight could literally just be the little engine that generates the spin.

      2. Jimmy2Cows Silver badge
        Boffin

        Re: ...treatment for brain changes and other detrimental health effects of space exposure...

        I liked Bab5. They should show it again.

        1. Greybearded old scrote
          Happy

          Re: ...treatment for brain changes and other detrimental health effects of space exposure...

          Out on Blu-Ray in December. I know what I'm buying me for Christmas.

          1. Jimmy2Cows Silver badge
            Angel

            Re: ...treatment for brain changes and other detrimental health effects of space exposure...

            Finally! It's about damn time!

          2. Chris Gray 1
            Go

            Re: ...treatment for brain changes and other detrimental health effects of space exposure...

            Hmm. A bunch of the early graphics on B-5 were done on Amigas with Video Toasters. I didn't have a Toaster, but my guess is that they didn't do 1080P resolution. So, blu ray would require upscanning. Might mess up the pattern done on the Vorlon ships. I've had B-5 on DVD for years, and with the strikes on in Hollywood, it might be time to play them again. Either that or continue on with "Murder She Wrote".

            1. Francis Boyle Silver badge

              Re: ...treatment for brain changes and other detrimental health effects of space exposure...

              You're probably right but one of the interesting things about Babylon 5 was watching the graphics steadily improve over the run. Pretty ropey at the beginning but by the end as good as any physical model work.

            2. Dizzy Dwarf

              Re: ...treatment for brain changes and other detrimental health effects of space exposure...

              Angela Lansbury was a Vorlon agent.

              How else do you explain the ruthless efficiency?

              1. SonofRojBlake

                Re: ...treatment for brain changes and other detrimental health effects of space exposure...

                "How else do you explain the ruthless efficiency?"

                The same way I explain the fear, surprise, an almost fanatical devotion to the Pope and the nice red uniforms.

                1. Anonymous Coward
                  Anonymous Coward

                  Re: ...treatment for brain changes and other detrimental health effects of space exposure...

                  "The same way I explain the fear, surprise, an almost fanatical devotion to the Pope and the nice red uniforms."

                  I didn't expect that!

                  1. SonofRojBlake

                    Re: ...treatment for brain changes and other detrimental health effects of space exposure...

                    Nobody does!

            3. DiViDeD

              Re: ...treatment for brain changes and other detrimental health effects of space exposure...

              From what I've seen so far of the Remastered set, the upscaling has been done pretty well.

              1. Greybearded old scrote

                Re: ...treatment for brain changes and other detrimental health effects of space exposure...

                I'm going on the assumption that they will have done a better job than my disc player can with the DVDs. Given the time/cpu constraints of doing it on the fly.

        2. John Brown (no body) Silver badge

          Re: ...treatment for brain changes and other detrimental health effects of space exposure...

          According to various sites, a B5 reboot is in pre-production, eg here but there's been pretty much nothing heard since, especially since the Warner/Discovery merger, which saw a lot of cancellations even of high profile already running projects, so I'm not holding my breath.

          On the other hand, if it does come to pass, then I hope to be pleasantly surprised since "Series creator J. Michael Straczynski is writing the pilot and will return as showrunner and executive producer"

          1. Claptrap314 Silver badge

            Re: ...treatment for brain changes and other detrimental health effects of space exposure...

            Oh my word. That's enough to get me to actually turn on a TV.....

    2. bombastic bob Silver badge
      Devil

      Re: ...treatment for brain changes and other detrimental health effects of space exposure...

      Most likely it would work but of course we need data to prove it.

      Just how hard would it be to make a 'habitat ring' that spins, for the ISS ? Gyro-stabilized and/or dual counter-rotation to overcome effects of friction and minimize the need for stabilizing thrusters...

      Single-rotor helicopters need tail rotors. So a solution for friction (and rotation/mass changes) on rotating artificial gravity would need to be able to produce some kind of counter-torque.to stabilize it.

      1. alisonken1

        Re: ...treatment for brain changes and other detrimental health effects of space exposure...

        That effect is due to using mechanical means (motor) to rotate mass (rotor) - of course the "... equal and opposite reaction..." effect kicks in.

        Possibly using something like balanced ion thrusters around the outer edge might do it - since the reaction is limited to the thruster location/angle and not a centralized mechanical mechanism.

  4. Eclectic Man Silver badge

    'Just One Thing'

    In the new series of 'Just One Thing' this morning, Dr Michael Mosley said that drinking several cups of tea every day was associated with stronger bones. Not sure whether the chemicals from tea are the same or similar to the one in the article.

    1. The Oncoming Scorn Silver badge
      Thumb Up

      Re: 'Just One Thing'

      Just don't get it from the Nutrimat.

    2. Arthur the cat Silver badge

      Re: 'Just One Thing'

      drinking several cups of tea every day was associated with stronger bones

      If that's the case I should be able to punch through walls by now. I have a strong tea-tropism, especially first thing in the morning.

  5. The Bobster

    Menagenagerie

    Space-induced bone loss?

    Moopsie!

  6. _Elvi_

    Sigh ...

    This will all end in tears.....

  7. Dr. G. Freeman

    I thought Stainless Steel Rats would be a solution.

    1. vogon00

      Damn you, sir!* You've just sentenced me to a weekend with Harry Harrison and Slippery Jim.

      *Actually, that's a 'Thank you':-)

      1. Is It Me

        Have you seen that they did a graphic novel of at least one of the Stainless Steel Rat stories?

        1. SonofRojBlake

          Slippery Jim was a regular character in 2000AD in my youth...

  8. A. Coatsworth Silver badge
    Mushroom

    I for one...

    >>not only prevented bone loss in the ISS' rodent residents, but even increased bone density.

    Who else had "rodents of unusual strenght from outer space", for the Apocalypse Bingo?

  9. Kev99 Silver badge

    Mayebe the space boffins will figure out a way to have the crew cabin rotate to simulate gravity of 1G or so.

    1. John Brown (no body) Silver badge

      The potential targets for a base or colony are the Moon and Mars, so there's no point in testing for more than 1/6th G or at worst 1/3rd G for long term studies.

      1. Claptrap314 Silver badge

        That's a huge point. If we are heading to Mars, we don't really need 1G in the ship. We still have to deal with low-G issues, but not microgravity.

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