Our takeaway from this: stay up-to-date with patches...
What updates and patches?
According to the article the bugs used by the exploit has been around since 2017 in all Windows (?) versions of MS Office supported back then, so that's 2010, 2013, 2016 plus I assume from this the bugs are still there in 2019, 2021 and 365; complete with the current (May 2022) security fixes.
>detect and remove these PDFs from incoming messages
With the level of ofuscation being used, are there some simple rules that can be used to detect these and only these PDFs? Or are we dependent upon spam filters and client AV/security software.
Hence my interpretation of the "takeaway" is: We have nothing to offer other than platitudes.