"...Sales will take place in regular businesses with much less risk to both the buyer and seller. ..."
I heard an interview with a serving drugs officer on the radio shortly after Ulbricht was jailed.
The officer, as I recall, didn't want to be named because of some of the things he was saying:
Transactions were safer because people weren't buying from random dealers in back alleys in the middle of the night, and weren't being ripped off/attempting to rip the dealer off;
The quality of narcotis actually improved notably because now people had real market choice and if yours weren't up to muster, there were plenty of other sellers. Purer product tends to lead to lower harm as it's the crap they're cut with that causes most immediate problems;
The prices went down which meant that pressure on buyers to maintain a level of purchase went down with it;
The dealers ran loyalty schemes and try-before-you buy schemes with usually accurate (or as accurate as could be expected) descriptions which lead to less harm due to taking something that was completely unknown.
He also admitted what everyone with half a brain already knows - the war on drugs is lost. It was lost before it ever really began!