Scale-out can not replace scale-up
There are workloads that only big 16/32-socket scale-up servers can handle, typically enterprise business software workloads such as SAP, databases, etc. In those workloads, scale-out clusters can not replace scale-up servers. Scale-out clusters can only handle embarassingly parallel workloads, such as clustered HPC number crunching workloads, and not all problems are easily parallelizable. For instance, look at the official SAP benchmark list, there are not a single cluster. The top record spot is held by a Unix SPARC server with 32 sockets scoring 844.000 saps. (SAP Hana is a cluster, used for analyzing static read-only data in RAM, so it is great for clusters. It is not fit for normal SAP workload OLTP, it is only fit for analyzing static data).
Only recently (a couple of months ago) there has been new large 16/32 socket x86 servers offerings by SGI (UV300H) and HP (Kraken). Until then, the largest scale-up x86 server were ordinary 8-socket servers sold by Oracle, HP, etc. There is a new breed of x86 servers now out on the market, the first generation 16/32-socket server ever. All earlier large x86 servers out there has been scale-out clusters such as SGI UV2000 server with 10.000s of cores, resembles a small supercomputer cluster. And SGI UV2000 customers have used it for clustered workloads.
The first generation of x86 scale-up servers will perform very poorly, trying to get rid of bugs and identify bottle necks. It takes a couple of generations before the x86 scale-up servers will start to perform ok. They dont stand a chance to large Unix servers and Mainframes today. For instance, the SAP Hana is a clustered workload, and is certified with SGI UV300H. I want to see non-clustered workloads running on the scale-up UV300H - and expect it to perform very poorly compared to large Unix boxes on scale-up workloads such as SAP. The problem with SAP is it scales awfully bad, because it is a non clustered workload. So going from 500.000 saps to 600.000 saps is a huge and very difficult step. Because SAP scales bad, and the SGI UV300H is first generation, I expect SGI UV300H score quite bad on SAP compared to large Unix boxes.