I'm been using unRAID, for about 4 years now, it has been extremely reliable.
Case – Cooler Master Elite – because it was what I had
Mainboard – Open Box: BIOSTAR A760G M2+ AM2+/AM2 AMD 760G Micro ATX AMD Motherboard – it was inexpensive and had low energy ratings…it also came with no I/O panel, didn’t bother me as it would not fit in my twisted and distorted space for it! I cut out a piece of foam and stuck in the space.
Drives – 2 x Western Digital Caviar Green WD6400AACS 640GB 7200 RPM SATA 3.0Gb/s 3.5″ Internal Hard Drive -Bare Drive – it was inexpensive, had low energy ratings, performance more than adequate for my planned unRaid usage
3 x Western Digital Caviar Green WD20EARS 2.0TB SATA 3.0Gb/s 3.5″ Internal Hard Drive -Bare Drive
Memory – 1 x Kingston 1GB 240-Pin DDR2 SDRAM DDR2 800 (PC2 6400) Desktop Memory Model KVR800D2N6/1G – inexpensive, performance more than enough
CPU – AMD Sempron 140 Sargas 2.7GHz Socket AM3 45W Single-Core Processor SDX140HBGQBOX – it was inexpensive, had low energy ratings, performance more than adequate for my usage
PSU – Rosewill Stallion Series RD400-2-SB 400W ATX V2.2 Power Supply – modified to slow fan down
UnRaidPlus 4.7.0 + unMenu – downloaded, installed onto a Kingston USB thumb drive I had around, didn’t need the features of the ‘Pro’ version, 6 drives will be enough for me, and as capacities increase over the years I will just keeping swapping out higher capacity models, instead of more disks overall, this way you are ‘refreshing’ the RAID every few years or so. Of course, if capacity is your goal, then nothing beats having 21 disks as an option!