Follow the money
If PayPal, MasterCard, and Visa are actually accepted, why aren't those accounts immediately shut down and the money that has already been paid traced from the buyer to the seller?
Cybercrooks have set up a web store that offers rented access to compromised machines on the TDSS/TDL-4 botnet. The latest version of the TDSS botnet agent bundles a component that turns compromised machines into a proxy connected to awmproxy.net. AWMproxy - which purportedly accepts payment via PayPal, MasterCard, and Visa …
The main problem would be the time between any siphoning and it's reporting. Most people only get a statement once a month and the perps can run a scrape for 24 hours then take the money and run. Once they have it as cash they could setup and re-run.
It's the usual problem where the black-hats have to act before the white hats can react and with electronic money you don't need much of a head start.
Set up a particular IP address for logging connections, rent the botnet, browse to that IP, identify botnet zombies, and either cut them off or clean them up. Even if the ISPs won't play ball, the big email services could simply reject all connections from those IPs.